Institute of Molecular Biology
Graduate
Admissions
University of Oregon
Tom Stevens, UO

Tom Stevens

Professor of Chemistry

B.A., San Francisco State University;
M.S., San Francisco State University;
Ph.D., California Institute of Technology

    Member of:
  • Institute of Molecular Biology

Office: Streisinger Hall Room 255C
Telephone: 541-346-5884

Lab: Streisinger Hall Room 255
Telephone: 541-346-4608

Chemistry Webpage
Email

Complete List of Publications

Davis-Kaplan, S.R., Compton, M.A., Flannery, A.R., Ward, D.M., Kaplan, J., Stevens, T.H. and L.A. Graham (2006) PKR1 encodes an assembly factor for the yeast V-type ATPase. J Biol Chem. 281 (42): 32025-32035.

Compton, M.A., Graham, L.A. and T.H. Stevens (2006) Vma9p (subunit e) is an integral membrane V0 subunit of the yeast V-ATPase. J Biol Chem. 281(22):15312-9

Lottridge, J.M., Flannery, A.R., Vincelli, J.L. and T.H. Stevens (2006) Vta1p and Vps46p regulate the membrane association and ATPase activity of Vps4p at the yeast multivesicular body. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6202-7

Bowers, K. and T.H. Stevens (2005) Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae.  Biochim. Biophys. Acta, 1744, 438-454.

Bowman E.J., L.A. Graham, T.H. Stevens, and B.J. Bowman (2004) The bafilomycin/concanamycin binding site in subunit c of the V-ATPases from Neurospora crassa and Saccharomyces cerevisiae. J Biol Chem 279:33131-8.

Malkus P., L.A. Graham, T.H. Stevens, and R. Schekman (2004) Role of vma21p in assembly and transport of the yeast vacuolar ATPase. Mol Biol Cell 15:5075-91.

Flannery A.R., L.A. Graham, and T.H. Stevens (2004) Topological characterization of the c, c', and c" subunits of the vacuolar ATPase from the yeast Saccharomyces cerevisiae. J Biol Chem 279:39856-62.

Graham L.A., A.R. Flannery, and T.H. Stevens (2003) Structure and assembly of the yeast V-ATPase. J Bioenerg Biomembr 35:301-12.

Kweon Y., A. Rothe, E. Conibear, and T.H. Stevens (2003) Ykt6p Is a Multifunctional Yeast R-SNARE That Is Required for Multiple Membrane Transport Pathways to the Vacuole. Mol Biol Cell 14:1868-81.

Conibear E., J.N. Cleck, and T.H. Stevens (2003) Links Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p. Mol Biol Cell 14:1610-23.

Conibear E. and T.H. Stevens (2002) Studying yeast vacuoles. Methods Enzymol. 351:408-32.

Kawasaki-Nishi S., K. Bowers, T. Nishi, M. Forgac, and T.H. Stevens (2001) The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis. J Biol Chem 276(50):47411-20.

Sagermann, M., T.H. Stevens, and B.W. Matthews (2001) Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae. PNAS 98(13):7134-9.

Gerrard, S.R., A.B. Mecklem, and T.H. Stevens (2000) The yeast endosomal t-SNARE, Pep12p, functions in the absence of its transmembrane domain. Traffic 1(1):45-55.

Conibear E. and T..H. Stevens (2000) Vps52p, Vps53p and Vps54p forms a novel multisubunit complex required for protein sorting at the yeast late Golgi. Mol Biol Cell 11(1):305-23.

Graham, L.A., B. Powell, and T.H. Stevens (2000) Composition and assembly of the yeast vacuolar H+-ATPase complex. J Exp Biol 203:61-70.

Gerrard, S.R., N.J. Bryant, and T.H. Stevens (2000) Vps21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment. Mol Biol Cell 11(2):613-26.

Gerrard, S.R., B.P. Levi, and T.H. Stevens (2000) Pep12p is a multifunctional yeast syntaxin that controls entry of biosynthetic endocytic and retrograde traffic into the prevacuolar compartment. Traffic 1(3):259-69.

Powell, B., L.A. Graham, and T.H. Stevens (2000) Molecular characterization of the yeast vacuolar H+-ATPase proton pore. J Biol Chem. 275(31):23654-60.

Bowers, K., B.P. Levi, F.I. Patel, and T.H. Stevens (2000) The sodium/proton exchanger Nhx1p is required for endosomal protein trafficking in the yeast Saccharomyces cerevisiae. Mol Biol Cell 11(12):4277-94.

Ungermann, C., G. Fischer von Mollard, O.N. Jensen, N. Margolis, T.H. Stevens, and W. Wickner (1999) Three v-SNAREs and two t-SNAREs are essential for homotypic vacuole fusion. J Cell Biol 145:1435-42.

Zheng, H., G. Fischer von Mollard, V. Kovaleva, T.H. Stevens, and N.V. Raikhel (1999) The Plant v-SNARE AtVTI1a Likely Mediates Vesicle Transport from the TGN to the Prevacuole. Mol Biol Cell 10:2251-64.

Fischer von Mollard, G. and T.H. Stevens (1999) The Saccharomyces cerevisiae: v-SNARE Vti1p is required for multiple transport pathways to the vacuole. Mol Biol Cell 10:1719-32.

Graham, L.A. and T.H. Stevens (1999) Assembly of the yeast vacuolar proton-translocating ATPase. J Bioener and Biomem 31:39-47.

Conibear, E. and T.H. Stevens (1998) Multiple sorting pathways between the late Golgi and the vacuole in yeast. Biochim Biophys Acta 1404:211-30.

Bryant, N.J., R.C. Piper, L.S. Weisman, and T.H. Stevens (1998) Retrograde traffic out of the yeast vacuole to the TGN occurs via the prevacuolar/endosomal compartment. J Cell Biol 142:651-63.

Graham, L.A., K.J. Hill, and T.H. Stevens (1998) Assembly of the yeast vacuolar H+-ATPase occurs in the endoplasmic reticulum and requires a Vma12p/Vma22p assembly complex. J Cell Biol 142:39-49.

Bryant, N.J., R.C. Piper, S.R. Gerrard, and T.H. Stevens (1998) Traffic into the prevacuolar/endosomal compartment of Saccharomyces cerevisiae: a VPS45-dependent intracellular route and a VPS45-independent, endocytic route. Eur J Cell Biol 76:43-52.

Fischer von Mollard, G. and T.H. Stevens (1998) A human homologue can functionally replace the yeast v-SNARE Vti1p in two vesicle transport pathways. J Biol Chem 273:2624-30.

Voos, W. and T.H. Stevens (1998) Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p. J Cell Biol 140:577-90.

Bryant, N.J. and T.H. Stevens (1998) Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole. Microbiol and Molec Biol Rev 230-47.

Jackson, D.D. and T.H. Stevens (1997) VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H+-ATPase assembly. J Biol Chem 272:25928-34.

Tomashek, J.J., L.A. Graham, M.U. Hutchins, T.H. Stevens, and D.J. Klionsky (1997) V1-situated stalk subunits of the yeast vacuolar proton-translocating ATPase. J Biol Chem 272:26787-93.

Stevens, T.H. and M. Forgac (1997) Structure, function and regulation of the vacuolar H+-ATPases. Ann Rev Cell and Devel Biol 13:779-808.

Piper, R.C., N.J. Bryant, and T.H. Stevens (1997) The membrane protein alkaline phosphatase is delivered to the vacuole by a route that is distinct from the VPS-dependent pathway. J Cell Biol 138:531-45.

Fischer von Mollard, G., S.F. Nothwehr, and T.H. Stevens (1997) The yeast v-SNARE mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p. J Cell Biol 137:1511-24.

Tellam, J.T., D.E. James, T.H. Stevens, and R.C. Piper (1997) Identification of a mammalian Golgi Sec1p-like protein; mVps45p. J Biol Chem 272:6187-93.

Bryant, N.J. and T.H. Stevens (1997) Two separate signals act independently to localize a yeast late-Golgi membrane protein through a combination of retrieval and static retention. J Cell Biol 136:287-97.

Hirata, R., L.A. Graham, A. Takatsuki, T.H. Stevens, and Y. Anraku (1997) VMA11 and VMA16 encode the second and third proteolipid subunits of the Saccharomyces cerevisiae vacuolar membrane H+-ATPase. J Biol Chem 272:4795-803.

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